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Zhi-Jie Liu Selected Research

bis(3',5')-cyclic diguanylic acid

1/2017The emerging roles of the DDX41 protein in immunity and diseases.
3/2014NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.
2/2013Binding of bacterial secondary messenger molecule c di-GMP is a STING operation.
12/2012The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response.
6/2012Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding.

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Zhi-Jie Liu Research Topics

Disease

7Neoplasms (Cancer)
01/2022 - 11/2014
4Bites and Stings (Sting)
03/2014 - 06/2012
3Pain (Aches)
01/2021 - 12/2010
3Neoplasm Metastasis (Metastasis)
01/2021 - 01/2020
3Nasopharyngeal Carcinoma
11/2020 - 01/2020
3Obesity
11/2019 - 10/2016
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2021 - 01/2019
2Schizophrenia (Dementia Praecox)
03/2020 - 01/2018
2Inflammation (Inflammations)
01/2020 - 10/2016
2Substance-Related Disorders (Drug Abuse)
01/2018 - 10/2016
2Type 2 Diabetes Mellitus (MODY)
01/2017 - 03/2016
1Multiple Sclerosis
12/2021
1Dehydration (Water Stress)
12/2021
1Psoriasis (Pustulosis Palmaris et Plantaris)
11/2020
1Disease Progression
10/2020
1Renal Cell Carcinoma (Grawitz Tumor)
10/2020
1Alzheimer Disease (Alzheimer's Disease)
03/2020
1Parkinson Disease (Parkinson's Disease)
03/2020
1Weight Loss (Weight Reduction)
02/2020
1Chronic Pain
11/2019
1Rectal Neoplasms (Rectal Cancer)
02/2019
1Contusions
01/2018
1Cardiotoxicity
04/2017
1Virus Diseases (Viral Diseases)
01/2017
1Coronary Artery Disease (Coronary Atherosclerosis)
03/2016
1Photophobia (Light Sensitivity)
01/2016
1Pneumonia (Pneumonitis)
01/2016
1Immune System Diseases (Immune Disorders)
11/2014
1Severe Fever with Thrombocytopenia Syndrome
06/2013
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
07/2012
1Hypersensitivity (Allergy)
12/2010

Drug/Important Bio-Agent (IBA)

5bis(3',5')-cyclic diguanylic acidIBA
01/2017 - 06/2012
4Proteins (Proteins, Gene)FDA Link
01/2020 - 06/2012
4DNA (Deoxyribonucleic Acid)IBA
01/2017 - 06/2012
4Phosphotransferases (Kinase)IBA
03/2014 - 06/2012
4Interferon Type IIBA
03/2014 - 06/2012
3InterferonsIBA
03/2014 - 12/2012
2CB2 Cannabinoid ReceptorIBA
01/2021 - 01/2019
2Pharmaceutical PreparationsIBA
03/2020 - 11/2014
2EnzymesIBA
12/2010 - 05/2009
1Interleukin-8 (Interleukin 8)IBA
01/2022
1Chemokine ReceptorsIBA
01/2022
1CannabinoidsIBA
12/2021
1SiliconIBA
12/2021
1CarbonIBA
12/2021
1Therapeutic UsesIBA
12/2021
1AlcoholsIBA
12/2021
1Histones (Histone)IBA
01/2021
1InterleukinsIBA
11/2020
1mesoglycanIBA
11/2020
1Biomarkers (Surrogate Marker)IBA
10/2020
1Cholinergic Agents (Cholinergics)IBA
03/2020
1GTP-Binding Proteins (G-Protein)IBA
02/2020
1lorcaserinIBA
02/2020
1LigandsIBA
02/2020
1Anti-Obesity Agents (Antiobesity Drugs)IBA
02/2020
1Protein Tyrosine PhosphatasesIBA
01/2020
1Calcium-Binding ProteinsIBA
01/2020
1GemcitabineFDA Link
01/2020
1ChemokinesIBA
01/2020
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2020
1AntioxidantsIBA
01/2020
1QuercetinIBA
01/2020
1NF-kappa B (NF-kB)IBA
01/2020
1Anti-Anxiety Agents (Anxiolytics)IBA
11/2019
1Cannabinoid Receptors (Cannabinoid Receptor)IBA
11/2019
1Antidepressive Agents (Antidepressants)IBA
11/2019
1Opioid Receptors (Opioid Receptor)IBA
11/2019
1CateninsIBA
01/2018
1Serotonin ReceptorsIBA
01/2018
15-HT2C Serotonin ReceptorIBA
01/2018
1Doxorubicin (Adriamycin)FDA LinkGeneric
04/2017
1Antineoplastic Agents (Antineoplastics)IBA
04/2017
1sanyang xuedaiIBA
04/2017
1Glucose (Dextrose)FDA LinkGeneric
01/2017
1Glucagon (Glukagon)FDA Link
01/2017
1EndocannabinoidsIBA
10/2016
1Fatty Acid DesaturasesIBA
03/2016
1Fatty Acids (Saturated Fatty Acids)IBA
03/2016
1ApigeninIBA
01/2016
1Tryptophan (L-Tryptophan)FDA Link
11/2014
1Leucine (L-Leucine)FDA Link
03/2014
1NucleotidesIBA
03/2014
1Recombinant ProteinsIBA
03/2014
1Nucleocapsid ProteinsIBA
06/2013
1Suramin (Suramin Sodium)IBA
06/2013
1Guanosine Monophosphate (5' Guanylic Acid)IBA
02/2013
1Pathogen-Associated Molecular Pattern MoleculesIBA
02/2013
1RNA (Ribonucleic Acid)IBA
02/2013
1cyclic diadenosine phosphateIBA
12/2012
1Transcription Factors (Transcription Factor)IBA
12/2012
1Small Interfering RNA (siRNA)IBA
12/2012
1Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA
06/2012
1Arachidonic Acid (Vitamin F)IBA
12/2010

Therapy/Procedure

2Radiotherapy
11/2020 - 01/2020
2Therapeutics
01/2016 - 02/2013
1Precision Medicine
10/2020
1Neoadjuvant Therapy
02/2019
1Consolidation Chemotherapy
02/2019
1Pain Management
10/2016